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风湿性疾病是一种常见和多发病,临床共同的特点是以骨关节和肌肉疼痛为主要症状,变化大,病程长,可导致劳动力丧失,甚至引起死亡。 非甾体抗炎药(NSAIDS)为目前用于风湿病治疗最广的药物,其共同的药理作用是通过抑制环氧化酶而抑制从花生四烯酸转化为前列腺素的过程,通过抑制前列腺素的合成而发挥消炎镇痛作用。消炎痛(吲哚美辛)作为这类药中疗效最好的药物,其副作用多,因此,临床应用受到限制。阿西米辛(Acemetacin)作为消炎痛的前体药,近年国内开始生产和应用,现将我院应用该药治疗62例风湿病患者疗效报道如下。
Rheumatic diseases is a common and frequently-occurring disease. The common clinical feature is that the main symptoms of joint pain and muscle pain are large changes and long course of illness, which can lead to labor loss and even death. Non-steroidal anti-inflammatory drugs (NSAIDS) is currently the most widely used drugs for rheumatism, and its common pharmacological effect is inhibition of cyclooxygenase and inhibit the conversion of arachidonic acid to prostaglandins through the inhibition of prostate The synthesis of anti-inflammatory and analgesic effect. Indomethacin (indometacin) as the best drug efficacy of these drugs, the side effects and more, therefore, the clinical application is limited. As a forerunner of indomethacin, Acemetacin has started to be produced and applied in China in recent years. Now, the curative effect of rheumatoid arthritis in our hospital is reported as follows.