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β_2微球蛋白(β_2-m)放射免疫测定已广泛应用于临床,对肾脏疾病的诊断、疗效及预后观察是一项灵敏、准确实用的指标。本文报告一组慢性肾病患者进行血液透析前后血清β_2-m的变化,并探讨β_2-m测定对血液透析的监护作用。报告如下。材料和方法一、正常对照组:52例(男28人,女24人),年龄18～56岁,平均38岁,身体健康,无心、肾疾患。二、慢性肾病组;56例(男25人,女21人),年龄16～59岁,平均39岁,病程1～13年,按照1985年全国第二届肾脏病学术会议临床分型标准分为;1.慢性肾小球肾炎组11例;2.慢性肾功能衰竭组31例;3.尿毒症组14例。
β 2 microglobulin (β_2-m) radioimmunoassay has been widely used in clinical diagnosis of renal disease, efficacy and prognosis is a sensitive, accurate and practical indicators. This paper reports a group of patients with chronic kidney disease before and after hemodialysis serum β_2-m changes, and explore β_2-m determination of hemodialysis guardianship. The report is as follows. Materials and Methods First, the normal control group: 52 cases (28 males and 24 females), aged 18 to 56 years, an average of 38 years old, good health, carelessness, kidney disease. Second, the chronic kidney disease group; 56 cases (25 males and 21 females), aged 16 to 59 years old, average 39 years old, duration of 1 to 13 years, according to the Second National Symposium on Nephrology in 1985 1. Chronic glomerulonephritis in 11 cases; 2. Chronic renal failure in 31 cases; 3. Uremia in 14 cases.