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目的:观察急性前壁心肌梗死患者心肌速度(V)、应变率(SR)的变化特点,探讨定量组织速度成像(QTVI)及应变率成像(SRI)技术定量评价急性心肌梗死(AMI)患者的左室局部梗死心肌功能的临床应用价值。方法:应用QTVI及SRI对20例AMI患者和30例正常人左室前壁及前间壁节段纵向收缩期(S)、舒张早期(E)及房缩期(A)的峰值速度(VS、VE、VA)、峰值应变率(SRS、SRE、SRA)进行测定,并以冠脉造影结果为标准进行对比分析。结果:VS:AMI组心梗室壁的不同水平均较正常对照组显著性减低;VE:除前间隔的心尖水平外,心梗室壁较正常对照组显著性减低;VA:前壁的不同水平及前间隔的心尖水平AMI组较对照组显著性减低;SRS、SRE:AMI组不同水平左室心梗室壁较对照组显著性减低;SRA:前壁的不同水平及前间隔的基底水平AMI组较对照组显著性减低(分别P<0.01和P<0.05)。结论:QTVI及SRI技术是临床无创、定量评价急性心肌梗死局部心肌功能的有效方法。
OBJECTIVE: To observe the changes of myocardial velocity (V) and strain rate (SR) in patients with acute anterior myocardial infarction (AMI), and to evaluate the clinical value of quantitative tissue velocity imaging (QTVI) and strain rate imaging (SRI) in patients with acute myocardial infarction Clinical Value of Left Ventricular Regional Myocardial Function in Patients with Local Infarction. Methods: Using QTVI and SRI, the peak systolic velocity (S), early diastolic (E) and contractile velocity (A) of 20 patients with AMI and 30 normal subjects were measured. VE, VA), peak strain rate (SRS, SRE, SRA) were measured and compared with coronary angiography results as a standard comparative analysis. Results: The levels of myocardial infarction in VS: AMI group were significantly lower than those in normal control group. VE: In addition to the apex level of anterior septum, myocardial infarction wall was significantly lower than that in normal control group. VA: AMI group was significantly lower than that of the control group in AMI group; SRS, SRE: AMI group LV levels of left ventricular myocardial infarction significantly reduced compared with the control group; SRA: the anterior wall of the different levels and the anterior basal level The AMI group was significantly lower than the control group (P <0.01 and P <0.05, respectively). Conclusion: The QTVI and SRI techniques are clinically noninvasive and effective in quantitative evaluation of myocardial function in patients with acute myocardial infarction.