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据近期出版的《新英格兰医学杂志》报道,一项研究结果显示早期1型糖尿病患者在接受CD3抗体治疗后其β细胞功能可维持18个月之久。来自于比利时布鲁塞尔公立大学的Bart Key-meulen博士及其同事报道说,Ⅰ型糖尿病是一种T细胞介导的自身免疫性疾病,可导致机体分泌胰岛素的β细胞功能缺损。
According to a recent issue of The New England Journal of Medicine, one study showed that beta-cell function in early-stage type 1 diabetes persists for 18 months after treatment with CD3 antibodies. Bart Key-meulen, Ph.D., from Brussels Public University in Belgium and colleagues report that type 1 diabetes is a T cell-mediated autoimmune disease that causes the body to secrete insulin-deficient beta-cells.