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分析临床及病理资料相似的乳腺癌术后长期存活组（ｎ＝２０）和２年内复发组（ｎ＝２０）细胞核ＤＮＡ含量。结果：两组按临床分期，Ⅰ、Ⅱ期与Ⅲ期间的ＤＮＡ含量相差显著（Ｐ＜０．０５）；按病理组织学分级，各组间均有非常显著的差异（Ｐ＜０．０１）。２０对配对病例中，１４对ＤＮＡ含量相差显著，复发者明显高于存活者（Ｐ＜０．０５）；另６对无显著差异（Ｐ＞０．０５）。由此提示，在影响乳腺癌预后的诸因素中，ＤＮＡ含量为独立的标示预后的生物学因素；而正确选择术式和规范手术操作也是提高乳腺癌生存率的重要因素。
The nuclear DNA content in the long-term survival group (n=20) and relapse group (n=20) after breast cancer surgery with similar clinical and pathological data were analyzed. Results: There was a significant difference in DNA content between the two groups according to the clinical stage (I, II, and III) (P<0.05). According to histopathological grade, there was a significant difference between the two groups (P<0.01). . Among the 20 paired cases, the difference in DNA content between the 14 pairs was significant, and the recurrence was significantly higher than the survivors (P<0.05); the other 6 pairs had no significant difference (P>0.05). This suggests that, among factors that affect the prognosis of breast cancer, DNA content is an independent biological factor that indicates prognosis; and proper choice of surgical procedures and standardized operation are also important factors in improving the survival rate of breast cancer.