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近年来AIDS病人患播散性乌型分支杆菌细胞内感染(DMAl)者不断增加,为鉴定HIV感染儿童乌型分支杆菌细胞内感染(MAl)的危险性以及感染后的临床特征和实验结果,本文作者对1986年12月至1991年4月期间196例HIV感染儿童的记录资料进行了分析,其中22冽为MAI感染者,另外65例MAI血培养阴性者为对照组。对全部MAI感染者均应用叠氮胸腺嘧啶核苷(zidovudine)、双去氧嘌呤核苷(dideoxyinosine)或二者联合应用进行抗逆转录病毒治疗。实验组中除1例外均在死亡前得到诊断。
In recent years, AIDS patients with disseminated Mycobacterium ulcerans intracellular infection (DMAl) are increasing, in order to identify HIV-infected children with intra-urogenital infection of Mycobacterium (MAl) the risk as well as the clinical features and experimental results after infection, The authors analyzed data from 196 HIV-infected children between December 1986 and April 1991, of whom 22 were MAI-infected and 65 were negative controls for MAI blood culture. Zidovudine, dideoxyinosine, or a combination of both, were used for antiretroviral therapy in all MAI-infected individuals. All but one of the experimental groups were diagnosed before death.