论文部分内容阅读
目的探讨甲氨喋呤联合米非司酮治疗子宫切口疤痕妊娠的效果。方法我院妇产科收治的子宫切口疤痕妊娠患者130例,随机分为观察组和对照组各65例。观察组患者均给予甲氨蝶呤联合米非司酮治疗,对照组患者均给予甲氨蝶呤治疗。药物治疗两个疗程后,两组患者均宫腔镜电切术将妊娠组织切除。结果观察组患者的药物治疗成功率明显高于对照组患者(P<0.05);子宫切除率明显低于对照组患者(P<0.05);血HCG转阴时间和平均住院时间明显短于对照组患者(P<0.05)。结论甲氨喋呤联合米非司酮治疗子宫切口疤痕妊娠具有良好的效果,可以提高患者的子宫保全率,值得临床推广。
Objective To investigate the effect of methotrexate combined with mifepristone in the treatment of uterine incision scar pregnancy. Methods 130 cases of uterine incision scar pregnancy admitted to obstetrics and gynecology department of our hospital were randomly divided into observation group and control group of 65 cases. Patients in the observation group were given methotrexate combined with mifepristone, and patients in the control group were treated with methotrexate. After two courses of medication, both groups of patients underwent hysteroscopic resection of the pregnancy tissue. Results The success rate of medication in the observation group was significantly higher than that in the control group (P <0.05); the hysterectomy rate was significantly lower than that in the control group (P <0.05); the HCG negative time and average length of stay in the observation group were significantly shorter than those in the control group Patients (P <0.05). Conclusion Methotrexate combined with mifepristone in the treatment of uterine incision scar pregnancy has a good effect, can improve the patient’s uterine preservation rate, worthy of clinical promotion.