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用补阳还五汤治疗早期脑梗塞60例,检测治疗前后血清总超氧化物歧化酶(SOD)、丙二醛(MDA)水平,并与65例正常人对照。结果显示:治疗前SOD水平显著低于正常人(P<0.01),MDA则显著偏高(P<0.01);治疗后两指标与正常人无显著差异(P>0.05)。本方能通过清除自由基和抑制脂质过氧化反应达治疗目的。说明SOD、MDA可作为反映本方治疗效果的有价值的指标
Sixty patients with early cerebral infarction were treated with Buyang Huanwu Decoction. The levels of serum total superoxide dismutase (SOD) and malondialdehyde (MDA) were measured before and after treatment, and were compared with 65 healthy controls. The results showed that: before treatment, the level of SOD was significantly lower than that of normal people (P <0.01) and MDA was significantly higher (P <0.01); there was no significant difference between the two indexes after treatment (P> 0.05) . This side by removing free radicals and inhibit lipid peroxidation for therapeutic purposes. Description SOD, MDA can be used as a reflection of the therapeutic effect of this valuable indicator