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脑红素脑病所导致脑损伤及后遗症严重影响婴幼儿的生存质量,因此必须重视胆红素脑病新生儿期后异常症状及体征早期识别和干预、治疗,这对每位患儿的具体情况制定科学的诊疗策略,有助于患儿的康复。在争端方面包括:脑干听觉诱发电位(brainstem auditory evoked potential,BAEP)为早期发现胆红素神经毒性和监测病情发展的灵敏检测指标;脑MRI是评价胆红素脑病的重要手段之一,其成像特征及演变过程与预后有明显的相关性;应用全身运动质量评估除了预测患儿神经发育的结局,还可以对评估中发现患儿的异常运动模式,有针对性的指导家长在家中进行手法抑制。干预策略包括在新生期后需采取综合治疗模式治疗疾病导致的脑损伤,尤其注意对异常姿势的发展要有预见性,及时采取抑制-促通训练模式,减轻不随意运动障碍的程度,降低不随意运动型脑瘫的发生率,以达到最大程度的康复。
Brain injury caused by cerebral encephalopathy and sequelae seriously affect the quality of life of infants and young children, it must pay attention to neonatal bilirubin encephalopathy abnormal symptoms and signs of early identification and intervention, treatment, which is specific to each child’s development Scientific diagnosis and treatment strategies to help children recover. In the dispute, including: brainstem auditory evoked potential (BAEP) for the early detection of bilirubin neurotoxicity and monitor the development of sensitive detection indicators; brain MRI is an important means of evaluation of bilirubin encephalopathy, its Imaging characteristics and evolutionary process have a significant correlation with prognosis; Application of whole body exercise quality assessment In addition to predicting the outcome of children with neurodevelopmental disorders, children can also be found in the evaluation of abnormal movement patterns, targeted guidance to parents at home practices inhibition. Intervention strategies include the need to take a comprehensive treatment model after the neonatal period of disease-induced brain injury, with particular attention to the development of abnormal posture to have predictability, timely inhibition - to promote training mode to reduce the degree of involuntary movement disorders, reduce the level of Free movement of cerebral palsy incidence, in order to achieve maximum recovery.