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基于自然药学观药物体系思维构架中药药物本质认识论,以提高对中药药物本质与有效物质基础的认识水平,指导中药理想药物体系及其药物研究。应用科学论、还原论、系统论、整体观进行中药药物体系基本特性表征关联分析。研究结果表明:药物体系自然性、协同性、亲和性三大基本特性表征出中药药物物质有机关联整合效应状态及其自然亲缘关系规律与亲缘药物学架构,体现中药及其复方药物本质与有效物质基础内涵。因此,基于药物体系思维构架中药药物本质认识论,可从微观系统认识中药药物本质与有效物质基础内涵,并可指导中药理想药物研究,预知与发现中药新的药物体系与新的中药原,从而为临床拓展丰富新的中药理想药物体系及其药物。
Based on the natural pharmacy concept of drug system thinking structure of the nature of Chinese medicine Epistemology, in order to improve the understanding of the nature of Chinese medicine and the effective material base to guide the Chinese medicine ideal drug system and drug research. Applied science, reductionism, system theory, holistic view of the basic characteristics of traditional Chinese medicine drug drug system analysis of the relationship between characteristics. The results show that: the three basic characteristics of natural, synergistic and affinity of drug system characterize the organic integrated effect of drug substance in organic relation and the relationship between them and the relationship of kinship pharmacology, which reflect the essence and effectiveness of traditional Chinese medicine and its compound drugs Material basis of connotation. Therefore, based on the framework of medicine system, the theory of essence of Chinese medicine can be used to understand the essence of Chinese medicine and the substance of effective substance from the micro-system, to guide the research of ideal medicine of Chinese medicine, predict and discover the new Chinese medicine system and new Chinese medicine, Extensive clinical development of new traditional Chinese medicine ideal drug system and its drugs.