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目的:探讨溶血磷脂酸、D-二聚体检测在预测进展性脑卒中的应用效果。方法:选取我院在2012年4月~2013年4月收治的进展性脑卒中患者35例(研究组)、健康体检者35例(对照组)作为研究对象,对2组研究对象的D-二聚体、溶血磷脂酸水平进行检测、比较。结果:研究组患者的D-二聚体水平均>75μg/L,呈阳性;对照组研究对象的D-二聚体水平均<75μg/L,呈阴性;研究组患者的溶血磷脂酸、D-二聚体平均水平均显著高于对照组,P<0.05。结论:D-二聚体、溶血磷脂酸是体内早期血栓形成的重要分子标志物,通过检测D-二聚体、溶血磷脂酸水平,可为临床预测进展性脑卒中提供有效依据。
Objective: To investigate the effect of detecting lysophosphatidic acid and D-dimer in predicting progressive stroke. Methods: 35 patients (study group) and 35 healthy subjects (control group) with progressive stroke who were treated in our hospital from April 2012 to April 2013 were selected as the study subjects. The D- Dimers, lysophosphatidic acid levels were detected, compared. Results: The levels of D-dimer in the study group were both> 75μg / L, and the levels of D-dimer in the control group were all <75μg / L. The levels of D-dimer, D - dimer average levels were significantly higher than the control group, P <0.05. Conclusion: D-dimer and lysophosphatidic acid are important molecular markers of early thrombosis in vivo. D-dimer and lysophosphatidic acid levels can be used to provide an effective basis for clinically predicting progressive stroke.