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目的:分析研究急性ST段抬高型心肌梗死患者通过阿替普酶溶栓治疗的方法以及治疗效果,为临床提供依据。方法:选取2014年3月到2015年3月急性ST段抬高型心肌梗死患者资料70例实施回顾性分析,70例患者随机分为两组,观察组和对照组分别35例,观察组患者通过阿替普酶溶栓方式进行治疗,对照组患者通过尿激酶溶栓方式治疗,记录观察组和对照组患者临床治疗效果、不良反应以及冠状动脉再通率,将结果进行统计学分析。结果:观察组患者冠状动脉再通率显著高于对照组患者(P<0.05),具有统计学意义;观察组患者治疗效果显著优于对照组患者(P<0.05),具有统计学意义;观察组出现不良反应几率显著低于对照组患者(P<0.05),具有统计学意义。结论:针对急性ST段抬高型心肌梗死患者通过阿替普酶进行溶栓治疗效果显著,安全可靠,应该在临床中大力推广使用。
OBJECTIVE: To study the method of thrombolytic therapy with alteplase in patients with acute ST-segment elevation myocardial infarction and its therapeutic effect, so as to provide the basis for clinical study. Methods: A retrospective analysis of 70 patients with ST-segment elevation myocardial infarction from March 2014 to March 2015 was performed. Seventy patients were randomly divided into two groups. The observation group and the control group were 35 cases and the observation group The patients in the control group were treated by thrombolysis with urokinase through the method of thrombolysis by alteplase. The clinical effects, adverse reactions and the recanalization rate of coronary artery in the observation group and the control group were recorded. The results were statistically analyzed. Results: The recanalization rate of coronary artery in the observation group was significantly higher than that in the control group (P <0.05), with statistical significance. The treatment group in the observation group was significantly better than the control group (P <0.05) The incidence of adverse reactions in the group was significantly lower than that in the control group (P <0.05), with statistical significance. Conclusion: Thrombolytic therapy with alteplase in patients with acute ST-segment elevation myocardial infarction has a significant effect and is safe and reliable. It should be vigorously promoted in clinic.