论文部分内容阅读
本文地方性克汀病65例患者,作外周血淋巴细胞染色体畸变率及SCE频率检查。证明地方性克汀病有明显遗传倾向,并发现亚二倍体和超二倍体出现频率较高;血液淋巴细胞染色体是不稳定的,SCE频率与健康人对照无显著差异。以上结果为地方性克汀病遗传因素研究提供依据。
65 cases of endemic cretinism in this article, for peripheral blood lymphocyte chromosome aberration rate and SCE frequency examination. Proved that endemic cretinism has a clear genetic predisposition, and found that subduploid and diploid higher frequency; blood lymphocyte chromosome is unstable, SCE frequency and healthy controls no significant difference. The above results provide the basis for the study of genetic factors of endemic cretinism.