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应用~3H标记血栓素B_2(TXB_2)放射免疫分析(RIA)技术,进行血小板生理功能,心、脑血管痉挛及血栓形成疾病的基础与临床研究工作,已有很多文献报告。由于~3H标记物需赖进口,价格昂贵。我们研制建成~(125)I标记TXB_2测定方法,并与~3H标记测定方法进行对照比较,两者结果一致。对于部分临床样品检测结果作了初步讨论。现将结果报告如下。
There are a lot of literature reports on the application of ~ 3H labeled radioimmunoassay (RIA) of thromboxane B 2 (TXB 2) in the basic and clinical research of platelet physiological function, cardiac and cerebral vasospasm and thrombosis. As ~ 3H markers need to be imported, expensive. We developed a method for the determination of ~ (125) I-labeled TXB_2 and compared it with the ~ 3H-labeled method, both of which are consistent. For some clinical samples test results made a preliminary discussion. The results reported below.