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目的:分析根除幽门螺杆菌(Hp)抗菌药物的应用情况,促进合理用药。方法:回顾性分析2009年1～12月荆门市第一人民医院住院消化性溃疡病例的根除Hp抗菌药物医嘱,统计抗菌药物种类、剂型和用法用量,评价用药合理性。结果:该院根除Hp的抗菌药物选择总体较为合理,但部分病例给予了《第三次全国幽门螺杆菌感染若干问题共识报告》未推荐的注射制剂,少数药物用法用量上存在问题。结论:应遵循专家共识意见及相关研究进展,并结合药物的剂型、药动学特点和不良反应等选择药物,确保临床合理用药。
Objective: To analyze the application of antimicrobial agents to eradicate Helicobacter pylori (Hp) and promote rational drug use. Methods: A retrospective analysis from January to December 2009, Jingmen First People ’s Hospital inpatients with peptic ulcer Hp antibacterial medicine orders, statistics antibacterial drugs, dosage forms and dosage, evaluation of drug rationality. Results: The overall choice of antibacterials for Hp eradication was reasonable. However, some cases did not recommend the injectable preparations for the “Consensus Report on the Third National Helicobacter Pylori Infection”, and there are some problems on the dosage and usage of a few drugs. Conclusion: The consensus of experts and relevant research progress should be followed, and combined with the drug dosage forms, pharmacokinetic characteristics and adverse reactions to choose drugs, to ensure that the clinical rational use of drugs.