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小鼠静注10mg/kgYC-93能显著抑制PCA反应,并能抑制大鼠颅骨骨膜肥大细胞的脱颗粒。本品对致敏豚鼠肺组织因抗原攻击所致的肺灌流量减少具有拮抗作用,使灌流量基本不变。并对致敏和正常豚鼠因抗原和组胺及SRS-A所诱导的喘息具有平喘作用。
The intravenous injection of 10mg / kg CY-93 in mice can significantly inhibit the PCA response and inhibit the degranulation of rat skull periosteal mast cells. This product sensitized guinea pig lung tissue due to antigen attack caused by decreased perfusion of the lungs have an antagonistic effect, so that perfusion was basically unchanged. And sensitized and normal guinea pigs due to antigens and histamine and SRS-A induced wheezing with asthma effect.