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采用HPLC测定莲心碱注射液中莲心碱的含量,以甲基莲心碱为内标,流动相为二氯甲烷-异丙醇-二乙胺(75∶25∶0.2),平均回收率为100.5%,并对其进行了光和热稳定性考察,t约为5.8个月,对光不稳定,提示该注射液应在低温、遮光条件下保存。
The content of liensinine in the lotusine injection was determined by HPLC. The internal standard of neferine was used. The mobile phase was dichloromethane-isopropanol-diethylamine (75:25:0.2). The average recovery was 100.5%, and its light and thermal stability study, t is about 5.8 months, unstable to light, suggesting that the injection should be stored at low temperature, shading conditions.