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目的了解2008-2012年六盘水市手足口病的流行现状,为制定防控策略提供依据。方法采用描述性流行病学方法对2008-2012年六盘水市手足口病疫情资料进行分析。结果 2008-2012年全市4个县(区、特区)共报告手足口病例9316例,发病率为63.37/10万,死亡10例,病死率为0.11%。其中钟山区发病数和发病率最高。4-7月为发病高峰。92.71%的病例是5岁以下婴幼儿,1岁组儿童发病率最高,并随年龄增大,发病率逐渐降低。男性发病率高于女性。2008-2012年全市共检测手足口病例标本853份,病毒核酸检测阳性率为61.90%,其中EV71检出阳性率34.23%;CA16检出阳性率16.65%;其他肠道病毒检出阳性率9.38%;检出EV71和CA16混合阳性率为1.64%。结论六盘水市手足口病发病有明显季节、年龄、性别差异,流行毒株以肠道病毒EV71和CA16为主,因此,要采取综合性预防控制措施预防该病的发生和降低流行强度。
Objective To understand the epidemic situation of hand-foot-mouth disease in Liupanshui City from 2008 to 2012 and provide basis for prevention and control strategy. Methods Descriptive epidemiological methods were used to analyze the epidemic data of HFMD in Liupanshui City from 2008 to 2012. Results A total of 9316 cases of hand, foot and mouth were reported in 4 counties (autonomous regions and municipalities) in 2008-2012. The incidence was 63.37 / 100 000, with 10 deaths and a case fatality rate of 0.11%. Among them, the highest incidence and incidence of Zhongshan disease. April-July peak incidence. 92.71% of the cases were infants under 5 years of age. The highest incidence was found in children aged 1 year and gradually decreased with age. The incidence of males is higher than that of females. A total of 853 cases of hand, foot and mouth disease were detected in the city from 2008 to 2012, and the positive rate of virus nucleic acid was 61.90%, of which the positive rate of EV71 was 34.23%, the positive rate of CA16 was 16.65% and the positive rate of other enterovirus was 9.38% The positive rate of EV71 and CA16 was 1.64%. Conclusion There are obvious seasonal, age and gender differences in HFMD in Liupanshui City. The epidemic strains are mainly enterovirus EV71 and CA16. Therefore, comprehensive prevention and control measures should be taken to prevent the occurrence and reduce the prevalence of HFMD.