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有9%梗阻性黄疸的患者术后发生急性肾功能衰竭并伴有内毒素血症.内毒素血症是吸收入门静脉系统的肠道内毒素增加和肝网状内皮系统的廓清能力下降所致.对于肝炎和肝肿瘤患者的一些研究表明乳果糖能防止或消除内毒素血症.本文对其在体外、在动物和人梗阻性黄疸时防止内毒素血症的作用做了研究.
In 9% of patients with obstructive jaundice, acute renal failure followed by endotoxemia resulted from an increase in intestinal endotoxins that absorbed the portal vein system and a decrease in the clearance capacity of the reticuloendothelial system. Some studies in patients with hepatitis and liver tumors show that lactulose can prevent or eliminate endotoxemia The role of lactulose in preventing endotoxemia in vitro and in animal and human obstructive jaundice was investigated.