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自1975年首次在东非和马达加斯加各发现2例抗氯喹恶性疟以来,非洲抗氯喹恶性疟的形势日趋严重,为此作者综述了1975～1982年间非洲抗氯喹恶性疟的情况,并对抗性监察方法和防制措施提出建议。〔抗性现状〕自1975年至1982年,非洲报告的抗氯喹恶性疟病例共34例,其中坦桑尼亚16例,肯尼亚9例,马达加斯加6例,莫桑比克、赞比亚及科摩罗各1例。上述病例为无免疫力的旅游者,他们的抗性程度多为RI,即经1.5g氯喹治疗后20～35天又出现原虫血症。现场流行病学调查采用7天体内试验法和体外试验法,其中以体内试验法为主。调
Since the first two cases of chloroquine-resistant falciparum malaria were found in East Africa and Madagascar in 1975, the situation of anti-chloroquine falciparum malaria in Africa has become increasingly serious. For this reason, the author reviewed the status of anti-chloroquine-resistant malaria in Africa from 1975 to 1982, And control measures to make recommendations. [Status of resistance] From 1975 to 1982, 34 cases of chloroquine-resistant falciparum malaria were reported in Africa, including 16 in Tanzania, 9 in Kenya, 6 in Madagascar, and 1 in each of Mozambique, Zambia and the Comoros. The above cases were non-immune tourists who were mostly resistant to RI, and parasitemia occurred 20 to 35 days after 1.5 g of chloroquine. Field epidemiological investigation using in vivo test method and in vitro 7 days, including in vivo test method. Tune