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目的探讨尖锐湿疣(CA)组织与人乳头瘤病毒(HPV)及解脲脲原体(Uu)感染的关系。方法分别对普通妇科门诊患者624例,性罪错妇女55例,吸毒妇女45例,正常女性52例共776例不同人群妇女进行尖锐湿疣流行情况调查。取阴道分泌物分别测Uu、淋球菌、滴虫、念珠菌感染情况,对CA阳性病例留取疣组织作标本,其他各组行宫颈刮片分别行HPV检测。结果CA组织HPV-6型与11型阳性检出率分别为84.1%与9.1%,HPV-6型与11型同时在一人身上存在占6.8%。CA组与正常组的HPV病毒检测有极明显差异(P<0.001)。结论CA组织与HPV及Uu感染密切相关,在控制HPV同时,必须治疗Uu感染。
Objective To investigate the relationship between the tissue of condyloma acuminatum (CA) and human papillomavirus (HPV) and Uu infection. Methods The prevalence of condyloma acuminatum in 624 cases of common gynecological clinic, 55 cases of sexual misconduct, 45 cases of drug abuse, 52 cases of normal women and 776 cases of different groups were surveyed. Take vaginal discharge were measured Uu, Neisseria gonorrhoeae, Trichomonas vaginalis, Candida infection, the CA-positive cases of wart tissue samples were taken, the other groups of cervical smears were HPV testing. Results The positive rates of HPV-6 and 11 in CA tissues were 84.1% and 9.1%, respectively. HPV-6 and 11 were both present in one person at 6.8%. There was a significant difference in the detection of HPV between CA group and normal group (P <0.001). Conclusion CA tissue is closely related to HPV and Uu infection. In the control of HPV, Uu infection must be treated.