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目的探讨罕见的肌纤维肉瘤(MFS)的临床病理特点与鉴别诊断。方法结合文献对肌纤维肉瘤的临床表现、组织病理学特征、治疗和预后进行探讨。结果患儿女性,12个月。肿块组织学显示肌纤维母细胞分化,梭形肿瘤细胞排列成束状,部分车辐状,肿瘤细胞中等核异型。结论恶性肌纤维肉瘤的肿瘤细胞光镜和免疫组化显示肌纤维母细胞的特征时应诊断为MFS,临床需与良性肌纤维母细胞增生性疾病、孤立性纤维性肿瘤、炎性肌纤维母细胞瘤、隆突性皮肤纤维肉瘤、恶性纤维组织细胞瘤、纤维肉瘤、平滑肌肉瘤及恶性蝾螈瘤相鉴别。局部复发常见,偶有转移,治疗方法为手术切除。
Objective To investigate the clinicopathological characteristics and differential diagnosis of rare myofibrosarcoma (MFS). Methods Combined with the literature on the clinical manifestations of myofibrosarcoma, histopathological features, treatment and prognosis. Results Children with children, 12 months. Histological examination showed myofibroblastic differentiation, spindle-shaped tumor cells arranged in a bundle, part of the car spoke, the tumor cells were nuclear anomalies. Conclusion Malignant myofibroma sarcoma tumor cells by light microscopy and immunohistochemistry showed that the characteristics of myofibroblasts should be diagnosed as MFS, the clinical need with benign myofibroblastic proliferative disease, solitary fibrous tumor, inflammatory myofibroblastoma, Lung Sudden skin fibrosarcoma, malignant fibrous histiocytoma, fibrosarcoma, leiomyosarcoma and malignant salamander tumor phase identification. Local recurrence is common, occasional transfer, treatment for surgical resection.