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目的：探讨连续性肾脏替代疗法（CRRT）在多器官功能障碍综合症（MODS）治疗中的价值和应用指针。方法：回顾性分析13例MODS病例因急性肾衰（ARF）采用CRRT治疗的病例，其中早期（器官累及≤2个）应用6例，中晚期（器官累及≥3个）应用7例。结果：CRRT对水潴留、高血钾、氮质血症的疗效确切，适合于不能搬动的MODS伴ARF的病人。同时CRRT还能清除炎症介质─肿瘤坏死因子-a（TNF－a），减轻器官的损害。早期应用者预后显著优于中晚期应用者。结论：CRRT在MODS治疗中不仅可部分替代肾脏的功能，还能清除炎症介质。早期应用可提高存活率。
Objective: To investigate the value of continuous renal replacement therapy (CRRT) in the treatment of multiple organ dysfunction syndrome (MODS) and its application. Methods: A retrospective analysis of 13 cases of MODS patients with acute renal failure (ARF) treated with CRRT cases, including early (organ involvement ≤ 2) application of 6 cases, advanced (organ involvement ≥ 3) application of 7 cases. Results: CRRT has definite curative effect on water retention, hyperkalemia and azotemia. It is suitable for patients with MODS and ARF who can not move. At the same time CRRT can also clear the inflammatory mediators ─ tumor necrosis factor-a (TNF-a), reduce organ damage. Early application of prognosis was significantly better than those in advanced applications. Conclusion: CRRT can not only partially replace the function of the kidney but also clear the inflammatory mediators during MODS treatment. Early application can improve the survival rate.