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目的比较新活素与硝酸甘油治疗心力衰竭的临床疗效。方法将240例心力衰竭患者随机分为观察组和对照组各120例,2组均给予吸氧、控制感染、控制心律失常等一般治疗,在此基础上,观察组给予新活素进行治疗,对照组给予硝酸甘油进行治疗,比较2组临床疗效及治疗前后的B型脑利钠肽(BNP)水平。结果治疗后观察组的总有效率为95.83%高于对照组的63.33%;治疗后2组BNP水平均低于治疗前,且观察组的BNP水平明显低于对照组,差异均有统计学意义(P<0.05)。结论新活素治疗心力衰竭较硝酸甘油有更好的临床疗效,能显著降低患者的BNP水平,值得临床推广应用。
Objective To compare the clinical efficacy of neomycin and nitroglycerin in the treatment of heart failure. Methods A total of 240 patients with heart failure were randomly divided into observation group (120 cases) and control group (120 cases). Both groups were given general treatment of oxygen inhalation, infection control and arrhythmia control. On the basis of this, The control group was given nitroglycerin for treatment. The clinical efficacy and the level of B-type natriuretic peptide (BNP) were compared between the two groups before and after treatment. Results After treatment, the total effective rate of the observation group was 95.83%, which was higher than that of the control group (63.33%). The levels of BNP in the two groups after treatment were lower than before treatment, and the levels of BNP in the observation group were significantly lower than those in the control group (P <0.05). Conclusion The new survivin treatment of heart failure has better clinical efficacy than nitroglycerin, can significantly reduce the level of BNP in patients, worthy of clinical promotion and application.