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目的：探讨卵巢癌CD44v6表达含量与其进展程度和转移的关系。方法：对64例不同临床期别及组织学类型的卵巢癌细胞CD44v6表达进行了流式细胞免疫学定量研究。结果：不同组织学类型卵巢癌细胞CD44v6表达差异无显著性（P＞0．05）；晚期卵巢癌细胞（（Ⅱ～Ⅲ期）CD44v6表达显著高于早期（Ⅰ期）（P＜0．05）；CD44v6高表达与术后复发及转移有显著相关性。结论：检测卵巢癌组织细胞CD44v6有助于预测卵巢癌进展程度、淋巴结转移的趋势以及评估预后。
Objective: To investigate the relationship between the expression of CD44v6 and its progression and metastasis in ovarian cancer. Methods: The expression of CD44v6 in 64 cases of different clinical stages and histological types was analyzed by flow cytometry. Results: There was no significant difference in the expression of CD44v6 in different histological types of ovarian cancer cells (P> 0.05). The expression of CD44v6 in advanced ovarian cancer cells (stage Ⅱ ~ Ⅲ) was significantly higher than that in early stage (P <0.05) ). The high expression of CD44v6 was correlated with the recurrence and metastasis.Conclusion: Detecting the expression of CD44v6 in ovarian cancer tissue can help predict the progression of ovarian cancer, the trend of lymph node metastasis and evaluate the prognosis.