地中海贫血,简称“地贫”,好发于地中海沿岸、美国黑人人群和印度次大陆等地区,我国南方发病率也很高,尤其是广西,地贫基因的携带率高达20%,故产前基因诊断地贫就显得尤为重要。产前基因诊断包括胎儿DNA的取样和胎儿DNA的基因分析。胎儿DNA的取样技术主要有创伤性和无创伤性取 Mediterranean anemia, referred to as “thalassemia”, occurs in the Mediterranean coast, the African American population and the Indian subcontinent and other regions, the incidence in southern China is also high, especially in Guangxi, thalassemia gene carrier rate as high as 20%, so the prenatal gene Diagnosis of thalassemia is particularly important. Prenatal genetic diagnosis includes sampling of fetal DNA and genetic analysis of fetal DNA. Fetal DNA sampling techniques are mainly traumatic and non-invasive to take