由于新生儿药化动力学的特点,目前一般认为最科学的方法是按该药血浓度的高低来确定其用药的剂量,以维持其有效的治疗浓度而又低于其中毒浓度为宜。因此,为了解新生儿应用苯巴比妥的剂量及其血浓度高低与止惊的关系,我们进行了以下的初步探讨: 一、研究对象新生儿惊厥病儿如破伤风,化脓性脑膜炎等共10例。其中以破伤风为主,因患儿的日龄等各方面的情况比较一致, Due to the characteristics of neonatal pharmacokinetics, it is generally considered the most scientific method is to determine the dose of the drug according to the concentration of the drug in order to maintain its effective concentration but lower than its toxic concentration is appropriate. Therefore, in order to understand the neonatal application of phenobarbital dose and the relationship between the level of blood concentration and the only surprise, we conducted the following preliminary study: First, the study of neonatal convulsions in children such as tetanus, purulent meningitis A total of 10 cases. Of which tetanus-based, due to the age of children and other aspects of the situation is more consistent,