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一、病例资料患者男,66岁。于1991年确诊慢性粒细胞白血病。于2000年8月因急淋变长期住我院。入院后行DOAP,DVLP 方案化疗2疗程达 CR,一月后复发再次行 COAP、VLP、DVLP 方案化疗均达PR。于2001年5月19日行 VLP 方案化疗(VCR 2mg+0.9%氯化钠40ml,静脉d_(1、8、15、21、)LASP10000U 静滴d_(19、28、Pred60mgd_(1～7)、30mgd_(8～14),第二次静推长春新碱时在左足背穿刺处发生渗漏致左足发生8cm×4cm 损伤,当时患者无明显不适,第二天患者局部出现红肿,第4天出现大片水泡,第8天水泡破裂脱落,局部形成溃
First, the patient information Male, 66 years old. In 1991 confirmed chronic myeloid leukemia. In August 2000 due to acute lymphoblastic live in our hospital for a long time. After admission, DOAP and DVLP regimens were given 2 courses of chemotherapy for CR. After January, recurrent COAP, VLP and DVLP regimens reached PR. On May 19, 2001, patients undergoing VLP chemotherapy (VCR 2mg + 0.9% sodium chloride 40ml, intravenous d_ (1,8,15,21) LASP10000U intravenous d_ (19,28, Pred60mgd_ 30mgd_ (8 ~ 14), the second intravenous injection of vincristine leakage occurred in the left foot and the back of the left foot injury occurred 8cm × 4cm, when patients with no obvious discomfort, the next day the local redness appeared in patients with the fourth day Large blisters, the first 8 days blisters fall off, the formation of ulceration