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目的探讨封闭抗体对复发性流产再次妊娠结局的临床意义。方法资料随机选取40例封闭抗体阳性的孕妇为研究组,40例封闭抗体阴性的孕妇为对照组,从确诊妊娠起,安胎治疗,同时分别在就诊0、48、96 h监测血HCG定量和孕酮数值,孕6周、孕8周和孕10周分别B超监测,比较两组妊娠结局。结果研究组的胎儿存活率明显高于对照组,两者比较差异均具有统计学意义(P<0.05)。结论封闭抗体对复发性流产再次妊娠有十分重要的参考价值以及临床价值。
Objective To investigate the clinical significance of blocking antibodies on the outcome of recurrent spontaneous abortion. Methods Data of 40 pregnant women with positive blocking antibody were randomly selected as the study group and 40 pregnant women with negative antibody as control group. The serum HCG levels were measured at the time of diagnosis of pregnancy and tocolysis and at 0,48 and 96 h of treatment respectively Progesterone values, 6 weeks pregnant, 8 weeks pregnant and 10 weeks pregnant were B-monitoring, comparing the two groups of pregnancy outcomes. Results The fetal survival rate of the study group was significantly higher than that of the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion Closed antibodies have very important reference value and clinical value for recurrent spontaneous abortion.