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目的:分析米非司酮与米索前列醇联合治疗稽留流产的疗效。方法:选取2013年10月-2014年10月我院收治的稽留流产患者120例,随机分为2组,联合组予以米非司酮联合米索前列醇治疗,常规组施以苯甲雌二醇注射液治疗,两组均行清宫术,比较两组镇痛效果、手术基本情况与不良反应情况。结果:联合组镇痛总有效率96.67%高于常规组68.33%,差异具有统计学意义(P<0.05);联合组手术基本情况优于常规组,差异具有统计学意义(P<0.05);联合组不良反应率48.33%明显低于常规组76.67%,差异具有统计学意义(P<0.05)。结论:采用米非司酮与米索前列醇联合治疗稽留流产效果显著。
Objective: To analyze the curative effect of mifepristone and misoprostol in the treatment of missed abortion. Methods: From October 2013 to October 2014, 120 cases of missed abortion admitted to our hospital were randomly divided into 2 groups. The combination group was given mifepristone combined with misoprostol. Alcohol injection treatment, both groups undergoing curettage, analgesic effect of two groups were compared, the basic situation of surgery and adverse reactions. Results: The total effective rate of analgesia in combined group was 96.67% higher than that in conventional group (68.33%), the difference was statistically significant (P <0.05). The basic situation of operation in combined group was better than that in routine group (P <0.05). Adverse reaction rate in combination group was 48.33%, which was significantly lower than that in conventional group (76.67%), the difference was statistically significant (P <0.05). Conclusion: The combination of mifepristone and misoprostol in treatment of missed abortion significantly.