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肿瘤相应性高血钙(Paraneoplastic hypercalcemia)系由非甲状旁腺组织异位产生和释放高血钙性体液介质而引起的。最常报导过的是妇科恶性肿瘤的肿瘤相应性综合症。1956年Plimpton和Gellhorn首先报导了伴有妇科恶性肿瘤的肿瘤相应性综合征,描述了两例继发于子宫内膜癌(1例不符合目前的标准)和1例发生于卵巢乳头状囊腺癌病例,并从文献收集了符合本文规定诊断标准的27个病例。也报导了继发于妇科肿瘤的醛固酮增多症,库兴氏综合征,低血糖症和红血球增多症。一、发生率最近Rees复习了易于掩盖肿瘤相应性综合征真实发病率的许多因素,是否仅考虑有临床症状的病例,还是将无临床症状而具
Tumor Necessity Paraneoplastic hypercalcemia is caused by the ectopic production and release of hypercalcemic humoral mediators from non-parathyroid tissue. The most commonly reported gynecological malignancy of tumor-responsive syndrome. Plimpton and Gellhorn first reported tumor-associated syndromes associated with gynecological malignancies in 1956, and described two cases of endometrial cancer secondary to endometrial cancer (1 not in compliance with the current standard) and 1 case of papillary cyst Cancer cases, and from the literature collected in line with the diagnostic criteria specified in this 27 cases. Also reported are aldosteronism secondary to gynecologic tumors, Cushing’s syndrome, hypoglycemia and polycythemia. First, the incidence Rees recently reviewed the easy-to-cover the true incidence of tumor-responsive syndrome, many factors, whether only consider the clinical symptoms of the case, or will have no clinical symptoms