肝硬变是慢性肝病的晚期,表现为肝实质细胞广泛破坏和再生,纤维结缔组织大量增生造成肝小叶和血管结构的无序化,结果常引起肝功能失代偿、食管静脉曲张、腹水、肝昏迷、上消化道出血及肝癌等致死性并发症。长期以来,肝硬变一直是消化病学研究的热点,尤其是针对肝硬变的各个并发症的发生机制及治疗,在近几年内均取得了突破性进展,为此,本期特邀请了吉林分社几位编委,就肝硬变的诊断及治疗,尤其是各个并发症的治疗进展,结合自己的研究和临床实践,作一系统介绍及精辟的综述,以期对临床有所裨益。 Cirrhosis is the late stage of chronic liver disease, the performance of extensive destruction and regeneration of liver parenchymal cells, fibrous connective tissue caused by a large number of hyperplasia of hepatic lobules and vascular structure of the disorder, the results often cause liver decompensation, esophageal varices, ascites, Hepatic coma, upper gastrointestinal bleeding and liver cancer and other fatal complications. For a long time, cirrhosis has been a hot point in the research of digestive diseases. Especially for the mechanism and treatment of various complications of cirrhosis, breakthroughs have been made in recent years. Therefore, this issue has invited Jilin Branch several editorial board, on the diagnosis and treatment of cirrhosis, especially the progress of the treatment of various complications, combined with their own research and clinical practice, a systematic introduction and insightful review, with a view to clinical benefit.