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为了评价思密达治疗婴幼儿急性轮状病毒肠炎的效果 ,选择我院肠道门诊年龄在6月～24月、病程在3天内、未使用过微生态药物和抗生素的急性轮状病毒肠炎患儿共182例 ,按随机编号分别给予口服思密达或庆大霉素片剂。结果共有165例完成本试验。思密达治疗组6天治愈率为98.9 % ,对照组为90.9 % ,两组差异有统计学意义 (精确概率P=0.026)。按时序检验思密达治疗组的平均疾病恢复时间为3.0天 ,对照组为4.0天 ,两组差异有统计学意义 (时序检验 χ2=10.78,P=0.001)。提示口服思密达治疗婴幼儿急性轮状病毒肠炎与对照组疗效相比 ,差异有显著性。
In order to evaluate the effect of Smecta on the treatment of acute rotavirus enteritis in infants and young children, we selected the patients with acute rotavirus enteritis who did not use microecological drugs and antibiotics during the course of 3 days in our hospital from June to 24 months. A total of 182 children, were randomized to give oral smectite or gentamicin tablets. Results A total of 165 patients completed the test. Smectite treatment group 6 days cure rate was 98.9%, 90.9% in the control group, the difference between the two groups was statistically significant (P = 0.026). According to the time-series test, the mean disease recovery time was 3.0 days in the Smectite-treated group and 4.0 days in the control group. The difference between the two groups was statistically significant (chi2 = 10.78, P = 0.001). Prompt oral smecta treatment of infants with acute rotavirus enteritis and the control group, the difference was significant.