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目的探讨血清肌钙蛋白T(cTnT)、超敏c-反应蛋白(hs-CRP)联合检测对不稳定心绞痛(UAP)患者近期预后判断的临床价值。方法对42例健康人、38例稳定心绞痛(SAP)和52例UAP患者分别进行血清cT-nT、hs-CRP检测,并对UAP患者随访6个月,观察心脏事件发生率。结果三组中UAP组血清cTnT、hs-CRP浓度均明显高于正常组和SAP组(P<0.01);心脏事件发生率也明显高于正常组(P<0.01)。结论 cTnT和hs-CRP测定可较敏感地反应微小心肌损伤,联合检测对判断UAP的预后有更好的临床价值。
Objective To investigate the clinical value of combined detection of serum cTnT and hs-CRP in the prognosis of patients with unstable angina pectoris (UAP). Methods Serum cT-nT and hs-CRP levels were measured in 42 healthy people, 38 patients with stable angina (SAP) and 52 UAP patients. UAP patients were followed up for 6 months to observe the incidence of cardiac events. Results Serum levels of cTnT and hs-CRP in UAP group were significantly higher than those in normal group and SAP group (P <0.01). The incidence of cardiac events was also significantly higher in UAP group than in normal group (P <0.01). Conclusions The cTnT and hs-CRP assays can reflect the micro myocardium injury more sensitively. The combined detection of cTnT and hs-CRP has a better clinical value in judging the prognosis of UAP.