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目的 为了明确无恶性胸水的肺癌患者胸膜腔内是否存在潜在癌细胞的播散转移即隐性恶性胸水 ,及其与肺癌患者预后、临床分期 (TNM)的关系。方法 1999年 1～ 6月对 30例肺癌患者进行术中胸腔冲洗液癌细胞检查 (PLC) ,即开胸后及关胸前两次冲洗 (分别为PLC1、PLC2 )。结果 本组PLC1阳性率为 5 6 6 % ,Ⅰ期肺癌PLC1阳性率为 5 7 14%。结论 即使无恶性胸水的肺癌患者或肺癌肿块被正常肺组织包裹 ,仍然有部分癌细胞播散转移至胸膜腔内 ,影响预后及病人生存期
Objective To clarify whether there is potential malignant pleural effusions in the pleural cavity of patients with lung cancer without malignant pleural effusion, and its relationship with the prognosis and clinical stage (TNM) of patients with lung cancer. Methods From January to June 1999, 30 cases of lung cancer patients underwent intraoperative thoracic washings of cancer cells (PLC), ie, two cycles of thoracotomy and chest closing (PLC1 and PLC2 respectively). Results The positive rate of PLC1 in this group was 56.6%. The positive rate of PLC1 in stage I lung cancer was 57.14%. Conclusion Even if patients with lung cancer without malignant pleural effusion or lung cancer masses are surrounded by normal lung tissue, some of the cancer cells still spread to the pleural cavity and affect the prognosis and patient survival