不同的疾病过程所引起的中枢神经系统(CNS)受累可表现为慢性脑膜炎综合征。此种综合征患者常呈亚急性或慢性,有发热、头痛、嗜睡、精神错乱、恶心、呕吐和颈强直。脑脊液(CSF)蛋白常增高,细胞增多常以淋巴细胞为主,糖可减少。这样的过程无好转或有发展,临床与 CSF 异常观察4周以上可视为慢性脑膜炎。多数病原所致未加治疗的慢性脑膜炎,其发病率与死亡率高,需要特殊的且常带有毒性的治疗,因而要求迅速作出诊断。 Central nervous system (CNS) involvement caused by different disease processes can manifest as chronic meningitis syndrome. Patients with this syndrome often subacute or chronic, fever, headache, drowsiness, confusion, nausea, vomiting and neck stiffness. Cerebrospinal fluid (CSF) protein is often increased, often increased lymphocytosis cells, sugar can be reduced. Such a process without improvement or development, clinical and abnormal CSF 4 weeks or more can be considered as chronic meningitis. Chronic meningitis, which is untreated by most pathogens, has a high morbidity and mortality and requires special and often toxic treatment, requiring prompt diagnosis.