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目的:研究治疗幽门螺杆菌阳性胃炎患儿采取铋剂四联和传统三联的临床效果。方法:将我院2010年4月-2016年2月收治的210例幽门螺杆菌阳性胃炎患儿,按照入院顺序分为两组,其中105例患儿采取铋剂四联作为研究组,另105例患儿采取传统三联作为对照组,比较两组患儿的临床效果。结果:经过对比两组患儿的临床效果看出,研究组幽门螺杆菌清除率84.76%以及总有效率92.38%,均比对照组清除率72.38%以及总有效率81.90%高;且研究组不良反应发生率7.62%,明显低于对照组不良反应发生率18.10%,差别有统计学意义(P<0.05)。结论:治疗幽门螺杆菌阳性胃炎患儿采取铋剂四联效果更好,患儿幽门螺杆菌的清除效果较高,改善患儿临床症状且安全性较高,具有临床推广及应用的价值。
Objective: To study the clinical efficacy of bismuth quadruplex and traditional triple therapy in children with Helicobacter pylori-positive gastritis. Methods: 210 children with Helicobacter pylori-positive gastritis treated in our hospital from April 2010 to February 2016 were divided into two groups according to admission sequence. Among them, 105 children took bismuth quadruple as research group and another 105 Cases of children to take the traditional triple as a control group, the clinical effects of two groups of children were compared. Results: After comparing the clinical effects of two groups of children, we found that the clearance rate of Helicobacter pylori in study group was 84.76% and the total effective rate was 92.38%, both of which were higher than the control group with a clear rate of 72.38% and the total effective rate was 81.90% The incidence of the reaction was 7.62%, which was significantly lower than that of the control group (18.10%), the difference was statistically significant (P <0.05). Conclusion: The treatment of Helicobacter pylori-positive gastritis in children with bismuth quadruple effect is better, children with high clearance effect of Helicobacter pylori to improve the clinical symptoms and safety of children with clinical promotion and application of value.