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痛经与月经过多是宫内节育器(IUCD)取出的最主要原因。IUCD 在宫腔内造成子宫内膜轻微的组织损伤,引起炎性反应,因此局部释放前列腺素。一般认为前列腺素的增加可能使带 IUCD 妇女发生痛经。以前报导使用双盲临床试用 Naproxen及安慰剂治疗原发痛经。Naproxen 能改善痛经,治疗期间月经量减少,本文报导的目的是评价 Na-proxen 应用于 IUCD_s 的妇女改善痛经及月经过多的效果。21例妇女使用 IUCD_s(铜 T 及铜7),皆有严重痛经,其中1例因手术未能参加最后的分析。所有妇女月经周期规律,妇科检查正常,7例未产,
Dysmenorrhea and menorrhagia is the most important reason for removal of the IUD. IUCD in the uterine cavity caused by minor tissue damage to the endometrium, causing inflammatory reactions, the local release of prostaglandins. It is generally believed that increased prostaglandins may cause dysmenorrhea in women with IUCD. Previous reports have used double-blind clinical trials of Naproxen and placebo in the treatment of primary dysmenorrhea. Naproxen improves dysmenorrhea and decreases menstrual flow during treatment. The purpose of this paper is to evaluate the effect of Na-proxen on IUCD_s women in improving dysmenorrhea and menorrhagia. Twenty-one women with IUCD_s (copper T and copper 7) had severe dysmenorrhea and 1 of them failed to participate in the final analysis due to surgery. All women’s menstrual cycle, gynecological examination was normal, seven cases did not produce,