一、病因和发病机理大仑丁性龈增生(以下简称DGN),虽常见于用大仑丁(苯妥英钠)治疗的癫(疒间)病员,但其病因与发病机理尚不很清楚。Kimball(1939)首次报道DGH病例时,认为牙跟的变化与维生素C缺乏有一定的关系。他对34名患儿进行了研究,指出凡发生跟增生者,血清中抗坏血酸含量降低。而持相反意见者认为,二者之 First, the etiology and pathogenesis Dunkin Ding gingival hyperplasia (hereinafter referred to as DGN), although commonly found in Dailun Ding (phenytoin sodium) treatment of epileptic patients, but its etiology and pathogenesis is not yet clear. When Kimball (1939) first reported the case of DGH, he thought the change in heel and vitamin C deficiency has a certain relationship. He conducted a study of 34 children, pointing out that where the occurrence of hyperplasia, serum ascorbate decreased. Those who hold the opposite view think both of them