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疼痛是晚期癌症患者的常见并发症.药物是治疗癌症疼痛的重要方法.本研究观察了盐酸吗啡控释片和硫酸吗啡控释片口服治疗癌症疼痛的止痛效果.现报告如下:1 材料和方法1.1病例1994年3月～1996年6月在我科治疗的晚期癌症患者85例,男50例,女35例;年龄17～76岁,平均年龄44岁;肺癌25例、头颈部癌17例、消化道恶性肿瘤12例、乳腺癌11例、妇癌11例、软组织肉瘤7例、其它2例.诊断均经病理学证实.l.2疼痛程度及原因本组患者均并发癌性疼痛.疼痛程度按卫生部《癌症病人三阶梯止痛疗法的指导原则》提出的标准,分为无痛,轻度、中度和重度疼痛.按疼痛程度0～10数字估量表评分,无痛为0,轻度疼痛为1～4,中度疼痛为5～7,重度疼痛为8～10.本组患者中度疼痛33例,疼痛评分5～7,平均值6.49;重度疼痛52例,疼痛评分8～10,平均值8.86.患者均接受过非阿片类止痛药治疗,其中16例用过可待因及其复
Pain is a common complication in patients with advanced cancer. Drugs are an important method for the treatment of cancer pain. This study investigated the analgesic effect of morphine hydrochloride controlled release tablets and morphine sulfate controlled release tablets on cancer pain. The report is as follows: 1 Materials and methods 1.1 Cases 85 patients with advanced cancer treated in our department from March 1994 to June 1996, 50 males and 35 females; aged 17 to 76 years, mean age 44 years; lung cancer in 25 cases, head and neck cancer 17 Cases, 12 cases of malignant gastrointestinal cancers, 11 cases of breast cancer, 11 cases of gynecological cancer, 7 cases of soft tissue sarcoma, and 2 other cases. The diagnosis was confirmed by pathology. l.2 Pain degree and causes of this group of patients with concurrent cancer pain The degree of pain is classified into painless, mild, moderate, and severe pain according to the standards set by the Ministry of Health “Guidelines for the Three-step Analgesic Therapy for Cancer Patients”. The score is 0 to 10 digits for the degree of pain, and the painlessness is 0. , Mild pain was 1 to 4, moderate pain was 5 to 7, and severe pain was 8 to 10. In this group, there were 33 cases of moderate pain, pain score 5 to 7, mean 6.49; 52 cases of severe pain, pain score 8 to 10, mean 8.86. Patients were treated with non-opioid analgesics, 16 of them were used Codeine and its complex