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前列腺移行细胞癌很少见,在大宗前列腺癌病例中其发病率约占2～3%。其特征是局部迅速恶化伴随广泛转移,生存期短。作者报道一例广泛转移的患者对化疗反应显著。患者57岁,因前列腺肿大、硬及不规则结节,排尿困难,经尿道前列腺活检,证实为中度分化的移行细胞癌。双侧睾丸切除一个月后,患者出现便秘、会阴部剧痛、间断直肠出血、呼吸困难等症状。检查后发现直肠有外在性压迫及双侧肺转移。行膀胱,直肠前后区的20次放疗(总量4,600rad),会阴疼痛和便秘完全缓解。由于频繁干咳、胸痛、静止时呼吸困
Transitional cell carcinoma of the prostate is rare, and its incidence is about 2 to 3% in cases of prostate cancer. It is characterized by rapid local deterioration with extensive metastasis and short survival. The authors reported a case of extensive metastases in patients who responded significantly to chemotherapy. The patient, 57 years old, was diagnosed with moderately differentiated transitional cell carcinoma due to enlarged prostate, hard and irregular nodules, difficulty urinating, and transurethral prostate biopsy. One month after bilateral testicular resection, the patient developed constipation, severe perineal pain, intermittent rectal bleeding, and difficulty breathing. After the examination, it was found that the rectum had external compression and bilateral lung metastases. Bladder, 20 radiotherapy in the front and back of the rectum (total 4,600 rad), complete relief of perineal pain and constipation. Due to frequent dry cough, chest pain, breathing difficulties while still