患者男性,53岁主诉血糖升高11年,加重伴下肢无力、咳嗽、咽痛1周现病史患者于11年前无明显诱因出现多尿、多饮、多食(具体量不详)、消瘦,体重下降20余斤,测尿糖(4+),自行口服“二甲双胍肠溶片0.25 tid”降糖治疗,未监测血糖。5年前因血糖控制差,就诊当地医院,诊断为糖尿病,改为“格列美脲2mg bid,二甲双胍肠溶片0.25 Male patients, 53-year-old chief complaint of elevated blood sugar for 11 years, aggravated with lower extremity weakness, cough, sore throat 1 week history of illness in 11 years ago, no obvious incentive for patients with polyuria, polydipsia, polyphagia (specific amount unknown) Weight loss of more than 20 pounds, urine test (4 +), self-administered ”metformin enteric-coated tablets 0.25 tid “ hypoglycemic treatment, no monitoring of blood glucose. 5 years ago due to poor blood glucose control, visit a local hospital, diagnosed with diabetes, to ”glimepiride 2mg bid, metformin enteric-coated tablets 0.25