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目的探讨新生儿暂时性三尖瓣返流的临床特点及血流动力学改变。方法总结２７例有临床表现，经超声心动图证实为中、重度三尖瓣返流，不伴其他心脏畸型的新生儿的临床及多普勒超声心动图特征。结果４例因呼吸窘迫、８例因青紫、２例因心动过速、１３例因心脏杂音而行超声心动图检查。患儿肺动脉收缩压平均（４１±１７）ｍｍＨｇ（１ｍｍＨｇ＝０．１３３ｋＰａ），１８例（６７％）＞３０ｍｍＨｇ。除３例心功能降低外，其他心内结构及功能正常。三尖瓣返流的发生与患儿的性别、出生体重、出生方式、孕周、母亲怀孕早期感染、用药、吸烟史、家族遗传病史等均无显著相关。随诊中除１例伴严重肺和消化道出血死亡，１例持续呼吸困难，第３周时仍有肺动脉高压外，其他２５例（９３％）于３～１０天（平均５５天）左右症状改善，体征消失。１６例每１～３天复查超声，１０例三尖瓣返流于５～１４天消失，６例２周时减轻。结论三尖瓣返流可引起青紫、呼吸、心跳加快、心脏杂音等临床表现，应与先天性心脏病鉴别。新生儿三尖瓣返流属自限性疾病，但对危重患儿仍应积极治疗。
Objective To investigate the clinical features and hemodynamic changes of transient tricuspid regurgitation in neonates. Methods The clinical manifestations of 27 cases were summarized. The clinical and Doppler echocardiographic features of neonates with moderate and severe tricuspid regurgitation without other cardiac malformations were confirmed by echocardiography. Results Four cases were diagnosed as respiratory distress, eight cases of bruising, two cases of tachycardia and thirteen cases of echocardiography due to heart murmur. Pulmonary systolic pressure in children with an average of (41 ± 17) mmHg (1mmHg = 0.133kPa), 18 cases (67%)> 30mmHg. In addition to 3 cases of cardiac dysfunction, the other structure and function of the normal heart. The occurrence of tricuspid regurgitation had no significant correlation with the gender, birth weight, birth pattern, gestational age, early pregnancy infection, medication, smoking history and family history of the patients. Follow-up in addition to a case of severe lung and gastrointestinal bleeding died, 1 case of persistent dyspnea, the third week there is still pulmonary hypertension, the other 25 cases (93%) in 3 to 10 days (an average of 5 5 days) Left and right symptoms improved, signs disappeared. Ultrasound was performed in 16 cases every 1 to 3 days, 10 cases of tricuspid regurgitation disappeared in 5 to 14 days, and 6 cases were relieved in 2 weeks. Conclusion The tricuspid regurgitation can cause bruising, breathing, rapid heartbeat, cardiac murmur and other clinical manifestations should be identified with congenital heart disease. Neonatal tricuspid regurgitation is a self-limiting disease, but should be actively treated in critically ill children.