HBV是一种DNA嗜肝病毒,可导致急性、慢性肝病。全世界大约有3．5～4亿HBV感染者,其中每年有近100万人死于肝硬化、肝癌。当肝病发展至肝硬化并肝功衰竭时,原位肝移植(OLT)是行之有效的手段。在过去,高H B V再感染率是导致移植失败的重要原因,HBV感染曾一度被认为是OLT的相对 HBV is a DNA hepatotropic virus that causes acute, chronic liver disease. There are about 350 to 400 million people infected with HBV in the world, of whom nearly 1 million die of cirrhosis and liver cancer every year. Orthotopic Liver Transplantation (OLT) is an effective method when liver disease develops into cirrhosis and liver failure. In the past, a high H B V re-infection rate was an important cause of graft failure, and HBV infection was once considered relative to OLT