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目的:探究临床上使用不同剂量胺碘酮治疗充血性心力衰竭(CHF)合并心律失常的疗效。方法:将我院20010年3月到2011年8月收治的98例患者随机分为两组,两组患者均进行常规治疗,在此基础上观察组(49例)第1周服用剂量为600mg/d,第2周剂量为400mg/d,第3周剂量为200mg/d,以后保持200mg/d的剂量至疗程结束;对照组1～3天剂量为600mg/d,4～7天剂量为400mg/d,第2周剂量为200mg/d,第3周剂量为100mg/d,此后维持剂量50mg/d至疗程结束。结果:观察组患者各项指标结果显示改善情况均比对照组好。结论:在对CHF合并心律失常患者进行治疗时,维持100mg/d剂量胺碘酮是比较安全有效的,值得在临床上推广。
Objective: To investigate the clinical efficacy of different doses of amiodarone in the treatment of congestive heart failure (CHF) with arrhythmia. Methods: 98 cases of our hospital from March 20010 to August 2011 were randomly divided into two groups, both groups were treated routinely, on the basis of observation group (49 cases) taking the first week of dose of 600mg / d, the second week of the dose of 400mg / d, the third week of the dose of 200mg / d, after the maintenance of 200mg / d dose to the end of the course of treatment; control group 1 to 3 days dose of 600mg / d, 4-7 days dose 400mg / d, the second week dose of 200mg / d, the third week of the dose of 100mg / d, then maintain the dose of 50mg / d to the end of treatment. Results: The indicators in the observation group showed that the improvement was better than the control group. Conclusion: In the treatment of CHF patients with arrhythmia, the maintenance of 100mg / d dose of amiodarone is more safe and effective, it is worth in the clinical promotion.