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目的分析红河州艾滋病病毒感染者和病人中艾滋病相关死亡的影响因素,为有针对性地采取艾滋病防治措施提供参考。方法根据“国家艾滋病综合防治信息系统”中HIV/AIDS病例报告、随访检测、抗病毒治疗随访资料,进一步核实建立数据库,使用Cox比例风险模型分析艾滋病相关死亡的影响因素。结果红河州HIV/AIDS病例中,报病时疾病状态为AIDS(HR=2.106,95%CI:1.906~2.326)、医疗机构就诊发现(HR=1.237,95%CI:1.102~1.388)、未接受过CD4+T淋巴细胞检测(HR=1.553,95%CI:1.390~1.735)、未接受抗病毒治疗(HR=5.007,95%CI:4.471~5.607)、男性(HR=1.568,95%CI:1.403~1.752)、报病时年龄30岁以上、高中及中专及以下文化程度的病例发生艾滋病相关死亡的风险更高。结论继续扩大HIV监测检测工作,及早发现HIV/AIDS病例,接受CD4+T检测和抗病毒治疗可降低HIV/AIDS的死亡风险,延长生存时间。
Objective To analyze the influencing factors of HIV-related death among HIV-infected persons and patients in Honghe Prefecture and provide reference for AIDS prevention and control measures. Methods According to the reports of HIV / AIDS cases, follow-up tests and follow-up data of anti-virus treatment in the “National AIDS Integrated Prevention and Control Information System”, the database was further verified and the influencing factors of AIDS-related death were analyzed using the Cox proportional hazard model. Results Among the HIV / AIDS cases in Honghe Prefecture, the disease status was AIDS (HR = 2.106, 95% CI: 1.906-2.326), and was found in medical institutions (HR = 1.237, 95% CI: 1.102-1.388) (HR = 1.553, 95% CI: 1.390-1.735), no anti-virus treatment (HR = 5.007, 95% CI: 4.471-5.607), male (HR = 1.568, 95% CI: 1.403 ~ 1.752). When the disease was reported to be over 30 years old, the risk of AIDS-related death was higher in cases of high school, secondary technical school or below. Conclusions Continuing to expand HIV monitoring and testing, early detection of HIV / AIDS cases and receiving CD4 + T test and antiviral therapy may reduce the risk of death from HIV / AIDS and prolong the survival time.