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本研究采用原子吸收光谱法，测定糖尿病４周大鼠膈肌组织中铜（Ｃｕ）、锰（Ｍｎ）、锌（Ｚｎ）、铁（Ｆｅ）的含量。并同时测定超氧化物歧化酶（ＳＯＤ）和丙二醛（ＭＤＡ）含量。结果显示糖尿病膈肌Ｃｕ（６．９２±０．６２μｇ／ｇｄｒｙｗｅｉｇｈｔ）．Ｚｎ（４１．８１±３．３６μｇ／ｇｄｒｙｗｅｉｇｈｔ）含量明显低于对照组（１２．８５±３．３４μｇ／ｇｄｒｙｗｅｉｇｈｔ，６２．９２±３．５５μｇ／ｇｄｒｙｗｅｉｇｈｔ）（Ｐ＜０．００１），Ｆｅ（９０．５６±５．２７μｇ／ｇｄｒｙｗｅｉｇｈｔ）明显高于对照组（４６．１１±３．５１μｇ／ｇｄｒｙｗｅｉｇｈｔ）（Ｐ＜０．００１），而Ｍｎ与对照组无明显差别（１．４９±０．２０μｇ／ｇｄｒｙｗｅｉｇｈｔｖｓ１．４２±０．２１μｇ／ｇｄｒｙｗｅｉｇｈｔ，Ｐ＞０．０５）。糖尿病膈肌组织ＳＯＤ（１１．６５±２．７８Ｕ／１００ｍｇ）明显低于对照组（２９．４０±２．７３Ｕ／１００ｍｇ）（Ｐ＜０．００１），ＭＤＡ（４７．７５±６．６６ｎｍｏｌ／１００ｍｇ）明显高于对照组（２１．９３±３．２７ｎｍｏｌ／１００ｍｇ）（Ｐ＜０．００１）。糖尿病膈肌组织Ｚｎ含量与其ＳＯＤ呈正相关（ｒ＝０．７０，Ｐ＜０?
In this study, the content of copper (Cu), manganese (Mn), zinc (Zn) and iron (Fe) in diaphragmatic muscle tissue of diabetic rats were measured by atomic absorption spectrometry. At the same time, the content of superoxide dismutase (SOD) and malondialdehyde (MDA) were determined. The results showed that diabetic diaphragm Cu (6.92 ± 0.62 μg / gdryweight). Zn (41.81 ± 3.36μg / gdryweight) was significantly lower than that of the control group (12.85 ± 3.34μg / gdryweight, 62.92 ± 3.55μg / gdryweight) (P <0.001) .56 ± 5.27μg / gdryweight) was significantly higher than that of the control group (46.11 ± 3.51μg / gdryweight) (P <0.001), while there was no significant difference between Mn and the control group (1.49 ± 0.20μg / gdryweights 1.42 ± 0.21 μg / gdryweight, P> 0.05). Diastolic diaphragmatic tissue SOD (11.65 ± 2.78U / 100mg) was significantly lower than that of the control group (29.40 ± 2.73U / 100mg) (P <0.001), MDA (47.75 ± 6.66nmol / 100mg ) Was significantly higher than that of the control group (21.93 ± 3.27nmol / 100mg) (P <0.001). The content of Zn in diabetic diaphragmatic tissue was positively correlated with its SOD (r = 0.70, P <0?