With the rapid developments in the field of information technology,the material research society is looking for an alternate scientific route to the traditional methods of trial and error in material research and process de-velopment.Machine learning emerges as a new research paradigm to accel-erate the application-oriented material discovery.Quantum dots are ex-panded as functional nanomaterials to enhance cutting-edge photonic technology.However,they suffer from uncertainty in industrial fabrication and application.Here,we discuss how machine learning accelerates the development of quantum dots.The basic principles and operation proce-dures of machine learning are described with a few representative examples of quantum dots.We emphasize how machine learning contributes to the optimization of synthesis and the analysis of material characterizations.To conclude,we give a short perspective discussing the problems of combining machine learning and quantum dots.