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由于内用药物而发生的皮疹称为药疹。药疹发病机理的种类很多:i.变态反应性:大部分药疹属于此种类型,它与使用剂量无关,是与药物原有药理作用完全无关系的皮疹,在被致敏个体,可因极少量致病药物,再次出现同一病状。2。中毒性:(1)药理学作用:如杭凝剂引起的紫斑,烟草酸引起的一过性红斑,麦角引起的坏疽等。(2)过量:在治疗量与中毒量相差不大时,常发生过量中毒。(3)蓄积作用:是长期用药而起,如银皮症或金皮症是银或金等重金属沉着于皮肤。长期使用砷剂后引起各
A rash due to internal medicine is called a drug eruption. Many kinds of pathogenesis of drug eruption: i. Allergy: most drug eruption belongs to this type, it has nothing to do with the dose, is completely independent of the pharmacological effects of the original rash in the primed individuals can be very small amount Pathogenic drugs, again the same symptoms. 2. Toxicity: (1) pharmacological effects: such as Hangzhou agent caused by purple spot, a transient erythema caused by tobacco acid, ergot caused by gangrene and so on. (2) overdose: the amount of treatment and poisoning is not much difference, often excessive poisoning. (3) Accumulation effect: is the long-term use of drugs, such as silver or golden skin disease is a heavy metal such as silver or gold on the skin. Long-term use of arsenic caused after each