论文部分内容阅读
目的研究酸蚀加碱热处理后种植体用钛合金(Ti6Al4V)表面微观结构的变化及在模拟体液中诱导钙磷沉积的能力。方法对钛合金表面分别采用打磨抛光、大颗粒喷砂酸蚀(SLA)、碱热、酸蚀加碱热处理,测试其表面理化性质变化,然后对其进行模拟体液(SBF)浸泡实验,采用带能谱分析的扫描电镜(SEM)及X射线衍射(XRD)观察分析沉积物。结果经过酸蚀加碱热处理的钛合金表面形成了多级孔洞的微观粗糙结构;经SBF浸泡实验后,其表面出现羟基磷灰石沉积,钙磷原子数百分比高于其他实验组(P<0.05)。结论酸蚀加碱热处理的钛合金表面同时具有良好的表面形态和生物活性,在模拟体液中浸泡可诱导羟基磷灰石形成,有利于骨结合的早期形成。
Objective To study the changes of microstructure of titanium alloy (Ti6Al4V) surface after acid etching and alkali treatment and the ability of inducing calcium and phosphorus deposition in simulated body fluid. Methods The surface of titanium alloy was polished, polished by large sand blasting (SLA), alkali heat, acid etching and alkali treatment. The surface physical and chemical properties of the titanium alloy were tested. Then the SBF immersion test was carried out. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) observation were used to analyze the sediments. Results Microstructure and roughness of multi-level holes were formed on the surface of titanium alloy after acid etching and alkali treatment. The hydroxyapatite deposition appeared on the surface after SBF immersion test, the percentage of calcium and phosphorus atoms was higher than other experimental groups (P <0.05 ). Conclusions The surface of titanium alloy treated by acid etching and alkali treatment has good surface morphology and biological activity. Soaking in simulated body fluid can induce the formation of hydroxyapatite, which is propitious to the early formation of bone.